ARTHROTEC should not be taken by women who are pregnant or who may become pregnant. ARTHROTEC may cause miscarriage or other serious complications.
Like all prescription nonsteroidal anti-inflammatory drugs (NSAIDs), ARTHROTEC may increase the chance of a heart attack or stroke that can lead to death. This chance increases with longer use and in people who have heart disease.
ARTHROTEC should not be used right before or after a heart surgery called a “coronary artery bypass graft (CABG).”
Also, like all prescription NSAIDs, ARTHROTEC can cause ulcers and bleeding in the stomach and intestines at any time during treatment, which can occur without warning and may cause death. The chance of this increases with age.
Do not take ARTHROTEC if you are allergic to diclofenac or misoprostol; if you had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine; and if you have active gastrointestinal bleeding, severe kidney or liver problems, or severe heart failure.
Tell your doctor if you have a history of high blood pressure, heart failure, fluid retention, ulcer disease, gastrointestinal bleeding, kidney disease or liver disease.
Prescription NSAIDs, including ARTHROTEC, can cause serious skin reactions which may cause death.
The most common side effects for ARTHROTEC are abdominal pain, diarrhea, indigestion, nausea, and gas.
ARTHROTEC should only be used exactly as prescribed at the lowest dose possible and for the shortest time needed.